AI overview
AI generated. Not medical advice.What it's for
Bone health, calcium balance, cardiovascular health
Who it may fit
Adults who get limited sun exposure or do not regularly eat vitamin K–rich foods and want simple daily bone and cardiovascular support.
Key actives per serving
- Vitamin D3 (cholecalciferol): 125 mcg (500 IU) (625% DV)
- Vitamin K2 (menaquinone-7, MK-7): 100 mcg
How to take
Adults take 1 capsule daily with any meal; do not exceed the suggested use. Fat-containing meals may support absorption of vitamin D3.
Diet / Allergen fit
Gluten Free; Non-GMO; No artificial flavors; No artificial colors; No milk, lactose, soy, or wheat.
Ingredients explained
Vitamin D3 (cholecalciferol)
Vitamin D3 is converted to its active form, which helps regulate calcium and phosphorus absorption for bone mineralization and overall calcium balance.
Caution: High intakes may increase calcium levels; consider total vitamin D from all sources and consult a professional if you have kidney issues or high calcium.
Vitamin K2 (menaquinone-7, MK-7)
MK-7 activates proteins like osteocalcin and matrix Gla protein that help direct calcium into bones and away from soft tissues.
Caution: Use caution if you take blood-thinning medications because vitamin K can affect normal blood clotting.
How they work together
Vitamin D3 supports calcium absorption from the gut, while MK-7 helps activate proteins that guide absorbed calcium into bones and away from arteries. Together they address both calcium uptake and proper calcium placement for bone and cardiovascular wellness.
Safety and tips
Label Warning: Consult a healthcare provider before use if you are pregnant, nursing, taking any medications, have a medical condition (especially hypercalcemia, kidney disease, or hyperparathyroidism), or are planning a medical procedure. Do not take with other supplements that contain vitamin D. Stop use and contact a physician if adverse reactions occur. Do not exceed the recommended dosage.
Who should be cautious: People on anticoagulants such as warfarin may need monitoring due to vitamin K content; discuss with a healthcare provider before use. Individuals with a history of kidney stones or high calcium levels may need personalized guidance. Since this product contains vitamin D at a higher dose, those taking other vitamin D products or high-calcium regimens should review total intake with a clinician. If combining with medications that may interact with vitamin K, consult a healthcare provider before use.
Storage: Store at room temperature.
iHerb Quality Promise
This product is guaranteed authentic and backed by our easy returns & refunds policy. Details
Overview
- Premium 2 in 1 Formula
- 125 mcg (500 IU) MK-7 | 100 mcg
- Bone Health & Cardiovascular Support
- Vitamin Supplement
- Gluten Free
- Non-GMO
- Guaranteed Quality
- Laboratory Tested
- Trusted Quality For Over 30 Years
21ST Century® D3+ K2 combines vitamin D3 with the most active form of vitamin K, two nutrients that support bone, teeth and cardiovascular health. Vitamin D is essential for absorption of calcium. Vitamin K is also important for the formation of healthy bones.
Specifications
- First available: 10/2025
-
Shipping weight:
0.1 kg
- Product code: CEN-28065
- UPC: 740985280652
- Package quantity: 120 count
- Dimensions: 14.9 x 6.1 x 4.7 cm , 0.1 kg
Suggested use
Consult your healthcare provider prior to taking high dose vitamin D supplements. As a vitamin supplement, adults take one (1) capsule daily with any meal or as directed by a healthcare provider. Do not exceed recommended dosage. Individual results may vary.
Other ingredients
Microcrystalline cellulose, oat fiber, gelatin capsule, dicalcium phosphate, magnesium silicate, magnesium stearate. Contains <2% of: silicon dioxide.
No artificial flavors, artificial colors, milk, lactose, soy or wheat.
Warnings
Consult a healthcare provider prior to use if pregnant, nursing, taking any medications, have a medical condition (especially hypercalcemia, kidney disease or hyperparathyroidism), or are planning a medical procedure. Do not take with other supplements that contain vitamin D, such as multivitamins. Stop use and contact a physician if adverse reactions occur.
Keep out of reach of children. Do not use if product appears to be tampered with or seal is broken.
Store at room temperature.
Disclaimer
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
| Supplement facts | ||
| Serving Size: 1 Capsule | ||
| Amount Per Serving | %Daily Value | |
| Vitamin D3 (as Cholecalciferol)(500IU) | 125 mcg | 625% |
| Vitamin K2 (as Menaquinone-7) (MK-7) | 100 mcg | ** |
| **Daily Value not established. | ||